The 2025 release The Ageless Brain is the fourth release by Dale E. Bredesen, MD. As in the first three works, this non-fiction tome focuses on Alzheimer’s. Those who have read the blog since 2017 know this topic is germane to the origination of Econogal.

Bredesen’s knowledge of the subject is extensive. Furthermore, he brings a positive, uplifting point of view to a subject that remains devastating for those diagnosed with the condition. However, a major point of his premise is the need for early testing and intervention. Fortunately, the interventions intertwine with healthy living.

The terms and language are technical. Yet I gained much from reading this text without specific knowledge of the jargon. Lay people can gain much from reading since the author wrote for a wide audience. Indeed, reaching the greater populace is critical to ending diseases such as Alzheimer’s and Parkinson’s and ALS.

Bredesen posits a healthy brain for those in their 70’s, 80’s, 90’s and beyond need not be the exception as I wrote in a Century of Life. For those of us who know (or knew) centurions with sharp minds, the premise is real and not far-fetched. Additionally, the author presents both data and actions which can reverse damage that has already occurred. His findings verified my own research, trials and observations.

Healthy living and common-sense play into protecting the brain. The author highlights things that are harmful for the brain as well as what is positive. The NFL and the pharmaceutical industry are just two of many that will not like a wide-spread adoption of the tools shared in The Ageless Brain.

Prevention plays a large part in protecting the thinking process. Some things are generalized. But Bredesen acknowledges the need for individualized plans when he states:

“Conceptually, when it comes to battling neurodegenerative diseases, our job is straightforward: Identify the needed supplies and ongoing demands for each disease (including age-related changes) and then address those needs with a personalized, precision-medicine protocol to ensure the demands are once again met by the supplies. p.26”

In other words, one size does not fit all. Medicine in general needs to adopt this attitude. The author believes each individual needs to have tests, including blood tests, from the age of 35 on. Thus, stopping the diseases long before they appear in the later stages of life.

Furthermore, there are two approaches to a healthy brain. The first involves protection from environmental toxins, unhealthy eating and lack of essential vitamins. In other words, keeping track of various inputs and how they impact outputs. This includes not only what you eat but when to eat. Bredesen suggests on page 189 that fasting should include a three-hour window before sleep. This allows for better rest, another key component for protecting the brain.

A second approach to having a healthy brain in the senior years is one of creating new paths in the brain. This is a frequent topic on Econogal. Bredesen devotes an entire chapter, The Brain’s Flex Factor, to learning new things to develop an ageless brain.

Neuroplasticity is the technical term for brain growth throughout life. Learning new things thus creating new neurons and pathways in the brain is on par with life-long learning. Bredesen takes the concept one step further. He suggests daily, monthly, and yearly challenges.

Daily challenges can be as simple as taking a new route to work, trying a new recipe, or switching from Sudoku to Logic Puzzles. The key is in changing the daily routine or pattern. Simple in thought, but possibly difficult to implement since there are 365 days in the year.

A monthly challenge could be reading all non-fiction instead of fiction or listening to the classical music station instead of country. The author states the key is to “…vary not just the activity but the type of activity from month to month. p. 207” So, a different reading material one month then followed by a month with a new outdoor activity. Thus, not just a switch of genres each month. The brain needs new experiences on a monthly basis.

Bredesen suggests the yearly challenge should be incorporated with a longer-term goal since it is so time consuming. Examples given include learning a new language. This lengthy process increases understanding which is a different part of the brain.

This review has just touched on the incredible information provided by Dr. Bredesen. This is a fantastic text that belongs in every library in the country. Furthermore, any family that is genetically predisposed to the various diseases of the brain will benefit from reading and sharing. My highest recommendation of 2025 so far goes to The Ageless Brain.